No. There are two ways to place Piezography ink: traditional (PK is in the PK channel) and “Piezography 2” where PK is in the Yellow channel.
PiezoDN curves are build for either configuration (check the “piezodn-p2” folders in the most recent download). The benefit of putting PK in the Yellow channel is that it allows you to do tradition Matte printing and PiezoDN neg / Piezography-gloss printing with out wasting ink by switching inks in the printer.
If you look at the manual under “inksets” it talks about what Piezography 2 configuration is. Piezodn Version 2 has curves that have been re-mapped for the “p2” ink configuration.
Best and happy new years all,